Patents

WO2005105801

"Preparation of pyrrolyl-substituted pyrido[2,3-d]pyrimidin-7-ones as phosphoinositide 3-kinase inhibitors”   Bruendl, M. M.; Gogliotti, R. D.; Goodman, A. P.; Reichard, G. A.  PCT Int. Appl.  (2005),  64 pp. WO  2005105801.
US20050245519

“Substituted morpholine compounds for the treatment of central nervous system disorders, their preparation and pharmaceutical compositions” Barta, N. S.; Glase, S. A.; Gray, D. L.; Reichard, G. A.; Simons, L. J.; Xu, W. U.S. Pat. Appl. Publ. (2005), 85 pp. US  20050245519.
WO2005100358

“Preparation of fused-ring heterocyclic NK1 antagonists for treatment of emesis, depression, anxiety and cough”  Xiao, D.; Palani, A.; Wang, C.; Tsui, H.-C.; Shih, N.-Y.; Reichard, G. A.  PCT Int. Appl.  (2005), 102 pp.  WO  2005100358.
WO2005023800

“Preparation of halo-substituted N-tetrazolylbenzo[b]thiophenecarboxamides with PI3K inhibitory activity as therapeutic agents” Connolly, M. K.; Gogliotti, R. D.; Hurt, C. R.; Reichard, G. A.; Visnick, M. PCT Int. Appl.  (2005), 82 pp.  WO  2005023800.

WO2004108715

“Preparation of N-tetrazolyl benzo[b]thiophenecarboxamides as phosphoinositide-3-kinase (PI3K) inhibitors for the treatment of cancer, inflammatory and cardiovascular diseases”  Bruendl, M. M.; Connolly, M. K.; Goodman, A. P.; Gogliotti, R. D.; Lee, H. T.; Plummer, M. S.; Sexton, K. E.; Reichard, G. A.; Visnick, M.; Wilson, M. W.  PCT Int. Appl. (2004), 101 pp. WO  2004108715. 
WO2004004722

“Preparation of 1-amido-4-phenyl-4-benzyloxymethylpiperidine derivatives and related compounds as neurokinin-1 (NK-1) antagonists for the treatment of emesis, depression, anxiety and cough” Shih, N.-Y.; Wang, S.; Reichard, G. A.; Xiao, D.; Wang, C. PCT Int. Appl. (2004),  91 pp. WO  2004004722.
WO2003078376

“Preparation of Cyclobutane Derivatives as NK1 Antagonists” Wrobleski, M. L.; Reichard, G. A.; Shih, N.-Y.; Xiao, D. PCT Int. Appl.  (2003), 160 pp.  WO  2003078376,  AN 2003:757661.

WO2003051840

“Preparation of Pyrrolidine and Piperidine Derivatives for Therapeutic Use as Neurokinin 1 (NK1) Receptor Antagonists” Paliwal, S.; Reichard, G. A.; Wang, C.; Xiao, D.; Tsui, H.-C.; Shih, N.-Y.; Arredondo, J. D.; Wrobleski, M. L.; Palani, A. PCT Int. Appl.  (2003), 133 pp.  WO  2003051840, CAN 139:69145.

WO2003042173

“Preparation of Arylpyrrolidinones as Neurokinin-1 (NK1) Antagonists” Reichard, G. A.; Paliwal, S.; Shih, N.-Y.; Xiao, D.; Tsui, H.-C.; Shah, S.; Wang, C.; Wrobleski, M. L. PCT Int. Appl.  (2003), 81 pp. WO  2003042173, CAN 138:401597.
WO2002089802

“Use of Neurokinin Receptor Antagonists to Treat Androgen-Dependent Diseases”  Leach, M. W.; Berardi, M. R.; Mirro, E. J.; Sinha, D.; Pachter, J.; Cartwright, M. E.; Reichard, G. A. PCT Int. Appl.  (2002), 42 pp, WO  2002089802, CAN 137:346212.

WO20010144200

“Preparation of 2-Imidazolidinones and Related Compounds as Selective Neurokinin Antagonists.”  Shih, N.-Y.; Shue, H.-J.; Reichard, G. A.; Paliwal, S.; Blythin, D. J.; Piwinski, J. J.; Xiao, D.; Chen, X.. PCT Int. Appl.  (2001), 108 pp. WO  20010144200, CAN 135:61331.
US Patent 6204265

"Preparation of Substituted Oximes and Hydrazones as Neurokinin Antagonists"  Reichard, G. A.; Shih, N.-Y.; Wang, D. U.S.  (2001), 36 pp.  US Patent 6204265,  CAN 134:237490 AN 2001:195199
US Patent 6063926

“Preparation of Piperidinylpentanone Oximes as Neurokinin Antagonists.” Reichard, G. A.; Alaimo, C. A.; Shih, N.-Y.; Ting, P. C.; Carruthers, N. I.; Lavey, B. J. U.S.  (2000),  67 pp.  US Patent 6063926 ,  CAN 132:334363.

US Patent 5945428

“Preparation of Spiroindolepiperazine Oximes, Hydrazones and Olefins as Neurokinin Antagonists.” Shih, N.-Y.; Reichard, G. A.; Aslanian, R. G.  U.S. (1999), 28 pp. US Patent 5945428  A  19990831  CAN 131:170343.
US Patent 5789422

“Preparation of Piperidinylaralkylamines as Neurokinin Antagonists.” Reichard, G. A.; Aslanian, R. G. U.S. (1998), 16 pp. US Patent 5789422, CAN 129:161494 AN 1998:534887.
US Patent 5696267

“Substituted Oximes, Hydrazones and Olefins as Neurokinin Antagonists." Reichard, G. A.; Aslanian, R. G.; Alaimo, C. A.; Kirkup, M. P.; Lupo, A., Jr.; Mangiaracina, P.; McCormick, K. D.; Piwinski, J. J.; Shankar, B. B.; Shih, N.-Y.; Spitler, J. M.; Ting, P. C.; Ganguly, A. Carruthers, N. I.  U.S.  (1997),  80 pp.  US  Patent 5696267  A  19971209  CAN 128:75317.