Pharmaceutical Companies
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| Clients | Knowledge Management | Resource & Technology Analysis | Drug Design | Leadership | Technical Expert: IP |
| Pharmaceutical Companies |  |
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Knowledge management in Pharmaceutical Companies typically benefits from robust enterprise solutions. However, challenges such as multi-site project team collaboration and global line function alignment may hinder progress due to poor communication. Despite significant investment in comprehensive data systems, scientific teams and management may not be fully exploiting these tools at their disposal. Scientists, hired to discover new drugs, are then overburdened with responsibilities for improving the interface between scientists and data. Our experience in working with effective data solutions that serve the needs of both scientists and scientific management gives you the advantage when we work with your in-house informatics team to optimize your knowledge management systems. This allows your in-house scientists to focus on the job of finding new drugs.
Return to the topResource and Technology Analysis
In order to remain competitive in the dynamic drug discovery arena, flexible resources are critical. With internal and outsourced resource options it is difficult to proactively adapt the appropriate investment to a dynamic portfolio. Cycle times, technological efficiency, and most importantly, scientific depth all impact delivery and overall return on investment. Furthermore, large organizations can face challenges of groupthink, internal politics and over-engineering the discovery process resulting in decreased efficiency. In order to frame resource investment decisions it is prudent to seek assistance from experienced external thought leaders to eliminate potential bias from the decision matrix. Our group provides in-depth resource value analyses to help inform your firm's resource decisions. Some examples of where we can help are:
- Effectiveness of internal vs. outsourced resource proposals
- Internal productivity analyses
- Technology acquisition
With the changing dynamic of the drug discovery industry, it is critical that larger pharmaceutical companies retain the very best of drug design talent in the industry. Shrinking R&D budgets invariably cycle back to R&D investment in order to avoid contacting the development pipeline. The costs involved with the cyclical nature of downsizing and hiring and retraining scientists are tremendous, both from an organizational and community perspective. Our team at Decision Informatics is in a position to bring in highly talented drug designers to complement your team of medicinal chemists, or to serve as a flexible resource as short, medium, or long term contract designers. We are available to assist in:
- HTS Library Analysis
- Hit Prioritization
- Lead Discovery
- SAR analysis and Chemoinformatics support
- Lead Optimization
- Analog Design (both singleton and library design)
- hERG Mitigation
- Toxicophore removal
With diversity of design approaches as a critical factor in raising the probability of success, it is important to regularly inject new ideas and perspectives into a design team. Please contact us to discuss how we can design compounds to help efficiently move your project forward.
Leaders are talented individuals who know where they are headed and can influence others to follow. Good judgement, engaging enthusiasm and a solid scientific foundation is paramount to success in the challenging environment of "time-bound results" oriented research. We have a track record of extremely effective leadership in many roles throughout the drug discovery process. We look forward to augmenting your leadership pool through the following roles:
- Consulting Director of Chemistry/Technology/Informatics
- Project Leader
- Executive Talent assessment
- Mentor to Executive Management and Project Leaders
Protecting intellectual property, from the discovery portfolio to launched products is critical for innovative pharmaceutical companies. Our experience in lead discovery, lead optimization, and chemical property space analysis provide the expertise to opine on the causal molecular variables critical to the design of drugs.
- Serve as an expert witness for your legal team
- Consult in the development of defensive scientific arguments